This gene is the putative transforming gene of avian sarcoma virus 17.
2.
Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrated.
3.
When a viral gene is introduced into the host cell and is sufficient to induce oncogenesis the creation of cancerous cells in the infected cell line, the gene is said to be a " viral transforming gene ".
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